HCSGD entry for CHCHD3

1. General information

Official gene symbolCHCHD3
Entrez ID54927
Gene full namecoiled-coil-helix-coiled-coil-helix domain containing 3
Other gene symbolsMINOS3 PPP1R22
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0001227RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcriptionIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIDA ISScellular_component
GO:0005743Mitochondrial inner membraneISScellular_component
GO:0006366Transcription from RNA polymerase II promoterIDAbiological_process
GO:0007007Inner mitochondrial membrane organizationIMPbiological_process
GO:0008053Mitochondrial fusionIMPbiological_process
GO:0019902Phosphatase bindingIDAmolecular_function
GO:0032947Protein complex scaffoldISSmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.91877527450.11367651310.99999024730.6463770793

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2546302346
GSE13712_SHEARUp0.0231447585
GSE13712_STATICDown-0.1407156472
GSE19018Down-0.2434325502
GSE19899_A1Down-0.1624220291
GSE19899_A2Down-0.0180526192
PubMed_21979375_A1Down-0.4310612962
PubMed_21979375_A2Down-0.2547060194
GSE35957Down-0.3835305096
GSE36640Down-0.3250617790
GSE54402Up0.1214405411
GSE9593Down-0.0859815683
GSE43922Down-0.2247272538
GSE24585Down-0.0861647760
GSE37065Up0.0395989894
GSE28863_A1Down-0.2485029387
GSE28863_A2Up0.3824877548
GSE28863_A3Down-0.0647669064
GSE28863_A4Up0.1678549723
GSE48662Down-0.6262067249

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-423-3pMIMAT0001340MIRT042475CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.