HCSGD entry for NSMCE4A
1. General information
| Official gene symbol | NSMCE4A |
|---|---|
| Entrez ID | 54780 |
| Gene full name | non-SMC element 4 homolog A (S. cerevisiae) |
| Other gene symbols | C10orf86 NS4EA NSE4A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000781 | Chromosome, telomeric region | IEA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006281 | DNA repair | IEA | biological_process |
| GO:0006310 | DNA recombination | IEA | biological_process |
| GO:0030915 | Smc5-Smc6 complex | IDA IEA | cellular_component |
| GO:2001022 | Positive regulation of response to DNA damage stimulus | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9475817180 | 0.0155924433 | 0.9999902473 | 0.2446159619 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0515895667 |
| GSE13712_SHEAR | Down | -0.0776159836 |
| GSE13712_STATIC | Down | -0.0589091002 |
| GSE19018 | Down | -0.0463312458 |
| GSE19899_A1 | Down | -0.4034899908 |
| GSE19899_A2 | Down | -0.6759687031 |
| PubMed_21979375_A1 | Down | -0.4179100108 |
| PubMed_21979375_A2 | Down | -0.7699523803 |
| GSE35957 | Down | -0.6980381539 |
| GSE36640 | Down | -0.8266548945 |
| GSE54402 | Down | -0.0659393021 |
| GSE9593 | Down | -0.4229579786 |
| GSE43922 | Down | -0.3495697159 |
| GSE24585 | Down | -0.3813266651 |
| GSE37065 | Up | 0.1178945372 |
| GSE28863_A1 | Up | 0.3028105377 |
| GSE28863_A2 | Up | 0.5897210551 |
| GSE28863_A3 | Down | -0.4189135324 |
| GSE28863_A4 | Up | 0.3149288624 |
| GSE48662 | Down | -0.7544789449 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT032268 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
