HCSGD entry for NSMCE4A


1. General information

Official gene symbolNSMCE4A
Entrez ID54780
Gene full namenon-SMC element 4 homolog A (S. cerevisiae)
Other gene symbolsC10orf86 NS4EA NSE4A
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000781Chromosome, telomeric regionIEAcellular_component
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006281DNA repairIEAbiological_process
GO:0006310DNA recombinationIEAbiological_process
GO:0030915Smc5-Smc6 complexIDA IEAcellular_component
GO:2001022Positive regulation of response to DNA damage stimulusIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.94758171800.01559244330.99999024730.2446159619

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0515895667
GSE13712_SHEARDown-0.0776159836
GSE13712_STATICDown-0.0589091002
GSE19018Down-0.0463312458
GSE19899_A1Down-0.4034899908
GSE19899_A2Down-0.6759687031
PubMed_21979375_A1Down-0.4179100108
PubMed_21979375_A2Down-0.7699523803
GSE35957Down-0.6980381539
GSE36640Down-0.8266548945
GSE54402Down-0.0659393021
GSE9593Down-0.4229579786
GSE43922Down-0.3495697159
GSE24585Down-0.3813266651
GSE37065Up0.1178945372
GSE28863_A1Up0.3028105377
GSE28863_A2Up0.5897210551
GSE28863_A3Down-0.4189135324
GSE28863_A4Up0.3149288624
GSE48662Down-0.7544789449

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-let-7b-5pMIMAT0000063MIRT032268ProteomicsFunctional MTI (Weak)18668040
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.