HCSGD entry for GNG2

1. General information

Official gene symbolGNG2
Entrez ID54331
Gene full nameguanine nucleotide binding protein (G protein), gamma 2
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004871Signal transducer activityIEAmolecular_function
GO:0005834Heterotrimeric G-protein complexIEA ISScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006112Energy reserve metabolic processTASbiological_process
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0007191Adenylate cyclase-activating dopamine receptor signaling pathwayISSbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0008283Cell proliferationIEAbiological_process
GO:0016020MembraneISScellular_component
GO:0030168Platelet activationTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0071377Cellular response to glucagon stimulusTASbiological_process
GO:0071380Cellular response to prostaglandin E stimulusISSbiological_process
GO:0071870Cellular response to catecholamine stimulusISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.79655273740.01397889520.99999024730.2324936829

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0917104510
GSE13712_SHEARDown-0.0230100386
GSE13712_STATICDown-0.0675688063
GSE19018Down-0.3821331501
GSE19899_A1Up0.0622494462
GSE19899_A2Down-0.3428612692
PubMed_21979375_A1Down-1.1970848571
PubMed_21979375_A2Down-0.1672142284
GSE35957Down-0.5302372864
GSE36640Down-1.9856475230
GSE54402Up0.4057115251
GSE9593Up0.0362153693
GSE43922Up0.3464932008
GSE24585Up0.7001463501
GSE37065Down-0.1427899184
GSE28863_A1Down-0.4691145653
GSE28863_A2Down-0.7229783999
GSE28863_A3Down-1.0594556948
GSE28863_A4Up0.0465437184
GSE48662Down-0.2798119974

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-30a-5pMIMAT0000087MIRT028498ProteomicsFunctional MTI (Weak)18668040
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.