HCSGD entry for GNG2

1. General information

Official gene symbolGNG2
Entrez ID54331
Gene full nameguanine nucleotide binding protein (G protein), gamma 2
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004871Signal transducer activityIEAmolecular_function
GO:0005834Heterotrimeric G-protein complexIEA ISScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006112Energy reserve metabolic processTASbiological_process
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0007191Adenylate cyclase-activating dopamine receptor signaling pathwayISSbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0008283Cell proliferationIEAbiological_process
GO:0016020MembraneISScellular_component
GO:0030168Platelet activationTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0071377Cellular response to glucagon stimulusTASbiological_process
GO:0071380Cellular response to prostaglandin E stimulusISSbiological_process
GO:0071870Cellular response to catecholamine stimulusISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.79655273740.01397889520.99999024730.2324936829

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0917104510
GSE13712_SHEARDown-0.0230100386
GSE13712_STATICDown-0.0675688063
GSE19018Down-0.3821331501
GSE19899_A1Up0.0622494462
GSE19899_A2Down-0.3428612692
PubMed_21979375_A1Down-1.1970848571
PubMed_21979375_A2Down-0.1672142284
GSE35957Down-0.5302372864
GSE36640Down-1.9856475230
GSE54402Up0.4057115251
GSE9593Up0.0362153693
GSE43922Up0.3464932008
GSE24585Up0.7001463501
GSE37065Down-0.1427899184
GSE28863_A1Down-0.4691145653
GSE28863_A2Down-0.7229783999
GSE28863_A3Down-1.0594556948
GSE28863_A4Up0.0465437184
GSE48662Down-0.2798119974

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-30a-5pMIMAT0000087MIRT028498ProteomicsFunctional MTI (Weak)18668040
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.