HCSGD entry for PODXL

1. General information

Official gene symbolPODXL
Entrez ID5420
Gene full namepodocalyxin-like
Other gene symbolsGp200 PC PCLP PCLP-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001726RuffleIDAcellular_component
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007155Cell adhesionIEAbiological_process
GO:0007162Negative regulation of cell adhesionISSbiological_process
GO:0016324Apical plasma membraneISScellular_component
GO:0016477Cell migrationISSbiological_process
GO:0022408Negative regulation of cell-cell adhesionISSbiological_process
GO:0030027LamellipodiumIDAcellular_component
GO:0030175FilopodiumIDAcellular_component
GO:0030335Positive regulation of cell migrationIDAbiological_process
GO:0031528Microvillus membraneISScellular_component
GO:0032534Regulation of microvillus assemblyISSbiological_process
GO:0033634Positive regulation of cell-cell adhesion mediated by integrinIDAbiological_process
GO:0036057Slit diaphragmISScellular_component
GO:0044297Cell bodyIEAcellular_component
GO:0045121Membrane raftIEAcellular_component
GO:0050900Leukocyte migrationIEAbiological_process
GO:0072015Glomerular visceral epithelial cell developmentISSbiological_process
GO:0072175Epithelial tube formationISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00227592040.06290513280.12793106380.4734767229

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3215383221
GSE13712_SHEARUp0.0869689501
GSE13712_STATICDown-0.8770151035
GSE19018Up0.4600827401
GSE19899_A1Up1.5445226675
GSE19899_A2Up2.9836831939
PubMed_21979375_A1Down-0.3961784338
PubMed_21979375_A2Up2.7031323610
GSE35957Down-0.5053000231
GSE36640Up0.2120818087
GSE54402Up1.7319906328
GSE9593Down-0.0774831146
GSE43922Up1.2764707740
GSE24585Down-0.6751449205
GSE37065Up0.9352292700
GSE28863_A1Down-0.5901832200
GSE28863_A2Down-0.1129151588
GSE28863_A3Down-0.1122340766
GSE28863_A4Up0.2091177850
GSE48662Down-1.6950823128

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT001522pSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
hsa-miR-124-3pMIMAT0000422MIRT002657MicroarrayFunctional MTI (Weak)15685193
hsa-miR-124-3pMIMAT0000422MIRT002657MicroarrayFunctional MTI (Weak)18668037
hsa-miR-145-5pMIMAT0000437MIRT021537Reporter assay;MicroarrayFunctional MTI21351259
hsa-miR-215-5pMIMAT0000272MIRT024915MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026206MicroarrayFunctional MTI (Weak)19074876
hsa-miR-26b-5pMIMAT0000083MIRT028791MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.