HCSGD entry for PODXL

1. General information

Official gene symbolPODXL
Entrez ID5420
Gene full namepodocalyxin-like
Other gene symbolsGp200 PC PCLP PCLP-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001726RuffleIDAcellular_component
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007155Cell adhesionIEAbiological_process
GO:0007162Negative regulation of cell adhesionISSbiological_process
GO:0016324Apical plasma membraneISScellular_component
GO:0016477Cell migrationISSbiological_process
GO:0022408Negative regulation of cell-cell adhesionISSbiological_process
GO:0030027LamellipodiumIDAcellular_component
GO:0030175FilopodiumIDAcellular_component
GO:0030335Positive regulation of cell migrationIDAbiological_process
GO:0031528Microvillus membraneISScellular_component
GO:0032534Regulation of microvillus assemblyISSbiological_process
GO:0033634Positive regulation of cell-cell adhesion mediated by integrinIDAbiological_process
GO:0036057Slit diaphragmISScellular_component
GO:0044297Cell bodyIEAcellular_component
GO:0045121Membrane raftIEAcellular_component
GO:0050900Leukocyte migrationIEAbiological_process
GO:0072015Glomerular visceral epithelial cell developmentISSbiological_process
GO:0072175Epithelial tube formationISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00227592040.06290513280.12793106380.4734767229

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3215383221
GSE13712_SHEARUp0.0869689501
GSE13712_STATICDown-0.8770151035
GSE19018Up0.4600827401
GSE19899_A1Up1.5445226675
GSE19899_A2Up2.9836831939
PubMed_21979375_A1Down-0.3961784338
PubMed_21979375_A2Up2.7031323610
GSE35957Down-0.5053000231
GSE36640Up0.2120818087
GSE54402Up1.7319906328
GSE9593Down-0.0774831146
GSE43922Up1.2764707740
GSE24585Down-0.6751449205
GSE37065Up0.9352292700
GSE28863_A1Down-0.5901832200
GSE28863_A2Down-0.1129151588
GSE28863_A3Down-0.1122340766
GSE28863_A4Up0.2091177850
GSE48662Down-1.6950823128

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT001522pSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
hsa-miR-124-3pMIMAT0000422MIRT002657MicroarrayFunctional MTI (Weak)15685193
hsa-miR-124-3pMIMAT0000422MIRT002657MicroarrayFunctional MTI (Weak)18668037
hsa-miR-145-5pMIMAT0000437MIRT021537Reporter assay;MicroarrayFunctional MTI21351259
hsa-miR-215-5pMIMAT0000272MIRT024915MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026206MicroarrayFunctional MTI (Weak)19074876
hsa-miR-26b-5pMIMAT0000083MIRT028791MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.