HCSGD entry for GSAP

1. General information

Official gene symbolGSAP
Entrez ID54103
Gene full namegamma-secretase activating protein
Other gene symbolsPION
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001540Beta-amyloid bindingIDAmolecular_function
GO:0005794Golgi apparatusIEAcellular_component
GO:0005802Trans-Golgi networkIDAcellular_component
GO:0030162Regulation of proteolysisIDAbiological_process
GO:0034205Beta-amyloid formationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00013601690.98076235710.03398773581.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3378452775
GSE13712_SHEARUp0.7661790557
GSE13712_STATICUp1.5672294692
GSE19018Down-0.3423806697
GSE19899_A1Up0.5800356837
GSE19899_A2Up3.2104613476
PubMed_21979375_A1Up2.5413478855
PubMed_21979375_A2Up3.7272826183
GSE35957Up0.1974806288
GSE36640Up1.8334677540
GSE54402Up1.3738484554
GSE9593Up0.8495522542
GSE43922Up1.3000315680
GSE24585Up0.7565718569
GSE37065Up0.5213130088
GSE28863_A1Down-0.1847003699
GSE28863_A2Up0.4045423650
GSE28863_A3Down-0.0210706806
GSE28863_A4Down-0.1726857355
GSE48662Down-0.1857220870

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.