HCSGD entry for GSAP

1. General information

Official gene symbolGSAP
Entrez ID54103
Gene full namegamma-secretase activating protein
Other gene symbolsPION
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001540Beta-amyloid bindingIDAmolecular_function
GO:0005794Golgi apparatusIEAcellular_component
GO:0005802Trans-Golgi networkIDAcellular_component
GO:0030162Regulation of proteolysisIDAbiological_process
GO:0034205Beta-amyloid formationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00013601690.98076235710.03398773581.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3378452775
GSE13712_SHEARUp0.7661790557
GSE13712_STATICUp1.5672294692
GSE19018Down-0.3423806697
GSE19899_A1Up0.5800356837
GSE19899_A2Up3.2104613476
PubMed_21979375_A1Up2.5413478855
PubMed_21979375_A2Up3.7272826183
GSE35957Up0.1974806288
GSE36640Up1.8334677540
GSE54402Up1.3738484554
GSE9593Up0.8495522542
GSE43922Up1.3000315680
GSE24585Up0.7565718569
GSE37065Up0.5213130088
GSE28863_A1Down-0.1847003699
GSE28863_A2Up0.4045423650
GSE28863_A3Down-0.0210706806
GSE28863_A4Down-0.1726857355
GSE48662Down-0.1857220870

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.