HCSGD entry for PLS1
1. General information
| Official gene symbol | PLS1 |
|---|---|
| Entrez ID | 5357 |
| Gene full name | plastin 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005200 | Structural constituent of cytoskeleton | TAS | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0051015 | Actin filament binding | TAS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5128537518 | 0.1743672201 | 0.9999902473 | 0.8081562951 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5090846008 |
| GSE13712_SHEAR | Down | -1.0730382629 |
| GSE13712_STATIC | Up | 0.7789926352 |
| GSE19018 | Down | -0.0106608149 |
| GSE19899_A1 | Down | -0.1277103157 |
| GSE19899_A2 | Down | -0.8146366716 |
| PubMed_21979375_A1 | Up | 0.2221850239 |
| PubMed_21979375_A2 | Down | -0.1299558773 |
| GSE35957 | Down | -0.2065198378 |
| GSE36640 | Down | -0.4173864081 |
| GSE54402 | Down | -0.1686668826 |
| GSE9593 | Down | -0.0481226137 |
| GSE43922 | Up | 0.0151850885 |
| GSE24585 | Up | 0.7273296192 |
| GSE37065 | Up | 0.0081242500 |
| GSE28863_A1 | Down | -0.1994518494 |
| GSE28863_A2 | Up | 0.0102929470 |
| GSE28863_A3 | Up | 0.0894169886 |
| GSE28863_A4 | Down | -0.0033313422 |
| GSE48662 | Down | -0.1852669609 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-106b-5p | MIMAT0000680 | MIRT020466 | Microarray | Functional MTI (Weak) | 17242205 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020716 | Reporter assay;Other | Non-Functional MTI | 20584899 |
| hsa-miR-1 | MIMAT0000416 | MIRT023752 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029352 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-320a | MIMAT0000510 | MIRT044764 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045231 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050998 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
