HCSGD entry for PLS1


1. General information

Official gene symbolPLS1
Entrez ID5357
Gene full nameplastin 1
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003779Actin bindingIEAmolecular_function
GO:0005200Structural constituent of cytoskeletonTASmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0051015Actin filament bindingTASmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.51285375180.17436722010.99999024730.8081562951

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.5090846008
GSE13712_SHEARDown-1.0730382629
GSE13712_STATICUp0.7789926352
GSE19018Down-0.0106608149
GSE19899_A1Down-0.1277103157
GSE19899_A2Down-0.8146366716
PubMed_21979375_A1Up0.2221850239
PubMed_21979375_A2Down-0.1299558773
GSE35957Down-0.2065198378
GSE36640Down-0.4173864081
GSE54402Down-0.1686668826
GSE9593Down-0.0481226137
GSE43922Up0.0151850885
GSE24585Up0.7273296192
GSE37065Up0.0081242500
GSE28863_A1Down-0.1994518494
GSE28863_A2Up0.0102929470
GSE28863_A3Up0.0894169886
GSE28863_A4Down-0.0033313422
GSE48662Down-0.1852669609

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-106b-5pMIMAT0000680MIRT020466MicroarrayFunctional MTI (Weak)17242205
hsa-miR-155-5pMIMAT0000646MIRT020716Reporter assay;OtherNon-Functional MTI20584899
hsa-miR-1MIMAT0000416MIRT023752Proteomics;MicroarrayFunctional MTI (Weak)18668037
hsa-miR-26b-5pMIMAT0000083MIRT029352MicroarrayFunctional MTI (Weak)19088304
hsa-miR-320aMIMAT0000510MIRT044764CLASHFunctional MTI (Weak)23622248
hsa-miR-186-5pMIMAT0000456MIRT045231CLASHFunctional MTI (Weak)23622248
hsa-miR-17-5pMIMAT0000070MIRT050998CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.