HCSGD entry for PHKA1
1. General information
| Official gene symbol | PHKA1 |
|---|---|
| Entrez ID | 5255 |
| Gene full name | phosphorylase kinase, alpha 1 (muscle) |
| Other gene symbols | PHKA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004553 | Hydrolase activity, hydrolyzing O-glycosyl compounds | IEA | molecular_function |
| GO:0004689 | Phosphorylase kinase activity | TAS | molecular_function |
| GO:0005516 | Calmodulin binding | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0005977 | Glycogen metabolic process | IEA TAS | biological_process |
| GO:0005980 | Glycogen catabolic process | TAS | biological_process |
| GO:0006006 | Glucose metabolic process | TAS | biological_process |
| GO:0006091 | Generation of precursor metabolites and energy | TAS | biological_process |
| GO:0006468 | Protein phosphorylation | TAS | biological_process |
| GO:0016310 | Phosphorylation | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0074203830 | 0.4421539683 | 0.2252732411 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0162301434 |
| GSE13712_SHEAR | Down | -0.2254988777 |
| GSE13712_STATIC | Up | 0.1920118562 |
| GSE19018 | Down | -0.3528517068 |
| GSE19899_A1 | Up | 0.3643435008 |
| GSE19899_A2 | Up | 0.9348224241 |
| PubMed_21979375_A1 | Up | 1.2067600917 |
| PubMed_21979375_A2 | Up | 1.5433390964 |
| GSE35957 | Up | 0.6325629124 |
| GSE36640 | Up | 2.0525438232 |
| GSE54402 | Up | 0.4999560330 |
| GSE9593 | Down | -0.0838054733 |
| GSE43922 | Up | 1.1526615605 |
| GSE24585 | Down | -0.5025389816 |
| GSE37065 | Up | 0.1732939814 |
| GSE28863_A1 | Down | -0.2546818510 |
| GSE28863_A2 | Up | 0.9702711536 |
| GSE28863_A3 | Down | -0.9687520927 |
| GSE28863_A4 | Down | -0.1356786080 |
| GSE48662 | Down | -0.2016975501 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-122-5p | MIMAT0000421 | MIRT023317 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027122 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027583 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031657 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-769-3p | MIMAT0003887 | MIRT039113 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-421 | MIMAT0003339 | MIRT039366 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042222 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050362 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051613 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052023 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
