HCSGD entry for PHKA1


1. General information

Official gene symbolPHKA1
Entrez ID5255
Gene full namephosphorylase kinase, alpha 1 (muscle)
Other gene symbolsPHKA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004553Hydrolase activity, hydrolyzing O-glycosyl compoundsIEAmolecular_function
GO:0004689Phosphorylase kinase activityTASmolecular_function
GO:0005516Calmodulin bindingIEAmolecular_function
GO:0005829CytosolTAScellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0005977Glycogen metabolic processIEA TASbiological_process
GO:0005980Glycogen catabolic processTASbiological_process
GO:0006006Glucose metabolic processTASbiological_process
GO:0006091Generation of precursor metabolites and energyTASbiological_process
GO:0006468Protein phosphorylationTASbiological_process
GO:0016310PhosphorylationTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00742038300.44215396830.22527324111.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0162301434
GSE13712_SHEARDown-0.2254988777
GSE13712_STATICUp0.1920118562
GSE19018Down-0.3528517068
GSE19899_A1Up0.3643435008
GSE19899_A2Up0.9348224241
PubMed_21979375_A1Up1.2067600917
PubMed_21979375_A2Up1.5433390964
GSE35957Up0.6325629124
GSE36640Up2.0525438232
GSE54402Up0.4999560330
GSE9593Down-0.0838054733
GSE43922Up1.1526615605
GSE24585Down-0.5025389816
GSE37065Up0.1732939814
GSE28863_A1Down-0.2546818510
GSE28863_A2Up0.9702711536
GSE28863_A3Down-0.9687520927
GSE28863_A4Down-0.1356786080
GSE48662Down-0.2016975501

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-122-5pMIMAT0000421MIRT023317MicroarrayFunctional MTI (Weak)17612493
hsa-miR-103a-3pMIMAT0000101MIRT027122SequencingFunctional MTI (Weak)20371350
hsa-miR-98-5pMIMAT0000096MIRT027583MicroarrayFunctional MTI (Weak)19088304
hsa-miR-16-5pMIMAT0000069MIRT031657SequencingFunctional MTI (Weak)20371350
hsa-miR-769-3pMIMAT0003887MIRT039113CLASHFunctional MTI (Weak)23622248
hsa-miR-421MIMAT0003339MIRT039366CLASHFunctional MTI (Weak)23622248
hsa-miR-484MIMAT0002174MIRT042222CLASHFunctional MTI (Weak)23622248
hsa-miR-25-3pMIMAT0000081MIRT050362CLASHFunctional MTI (Weak)23622248
hsa-let-7e-5pMIMAT0000066MIRT051613CLASHFunctional MTI (Weak)23622248
hsa-let-7b-5pMIMAT0000063MIRT052023CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.