HCSGD entry for PFKP


1. General information

Official gene symbolPFKP
Entrez ID5214
Gene full namephosphofructokinase, platelet
Other gene symbolsPFK-C PFKF
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:00038726-phosphofructokinase activityIEA ISS TASmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005829CytosolTAScellular_component
GO:00059456-phosphofructokinase complexIEAcellular_component
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0006002Fructose 6-phosphate metabolic processIEAbiological_process
GO:0006006Glucose metabolic processTASbiological_process
GO:0006096GlycolysisIEA TASbiological_process
GO:0032403Protein complex bindingIDAmolecular_function
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046835Carbohydrate phosphorylationISS TASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.92037442730.00168062380.99999024730.0786605684

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-1.0174534386
GSE13712_SHEARUp0.0769918925
GSE13712_STATICUp0.2509445431
GSE19018Up0.5898405640
GSE19899_A1Down-0.8855630380
GSE19899_A2Down-1.7346882412
PubMed_21979375_A1Down-1.0274085231
PubMed_21979375_A2Down-1.3411886575
GSE35957Down-1.6021425309
GSE36640Down-1.1662993971
GSE54402Up0.1724522503
GSE9593Down-0.6232096632
GSE43922Down-0.6704463361
GSE24585Down-0.7352961257
GSE37065Up0.0982190383
GSE28863_A1Down-0.2885695668
GSE28863_A2Up0.5893973116
GSE28863_A3Down-0.2458898255
GSE28863_A4Down-0.0057052332
GSE48662Down-0.3198805635

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-520a-3pMIMAT0002834MIRT007336Luciferase reporter assay//qRT-PCR//Western blotFunctional MTI23389994
hsa-miR-520bMIMAT0002843MIRT007337Luciferase reporter assay//qRT-PCR//Western blotFunctional MTI23389994
hsa-miR-520eMIMAT0002825MIRT007338Luciferase reporter assay//qRT-PCR//Western blotFunctional MTI23389994
hsa-miR-26b-5pMIMAT0000083MIRT030323MicroarrayFunctional MTI (Weak)19088304
hsa-miR-455-3pMIMAT0004784MIRT037818CLASHFunctional MTI (Weak)23622248
hsa-miR-615-3pMIMAT0003283MIRT039986CLASHFunctional MTI (Weak)23622248
hsa-miR-193b-3pMIMAT0002819MIRT041540CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.