HCSGD entry for PFKP
1. General information
| Official gene symbol | PFKP |
|---|---|
| Entrez ID | 5214 |
| Gene full name | phosphofructokinase, platelet |
| Other gene symbols | PFK-C PFKF |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003872 | 6-phosphofructokinase activity | IEA ISS TAS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005945 | 6-phosphofructokinase complex | IEA | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0006002 | Fructose 6-phosphate metabolic process | IEA | biological_process |
| GO:0006006 | Glucose metabolic process | TAS | biological_process |
| GO:0006096 | Glycolysis | IEA TAS | biological_process |
| GO:0032403 | Protein complex binding | IDA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046835 | Carbohydrate phosphorylation | ISS TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9203744273 | 0.0016806238 | 0.9999902473 | 0.0786605684 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.0174534386 |
| GSE13712_SHEAR | Up | 0.0769918925 |
| GSE13712_STATIC | Up | 0.2509445431 |
| GSE19018 | Up | 0.5898405640 |
| GSE19899_A1 | Down | -0.8855630380 |
| GSE19899_A2 | Down | -1.7346882412 |
| PubMed_21979375_A1 | Down | -1.0274085231 |
| PubMed_21979375_A2 | Down | -1.3411886575 |
| GSE35957 | Down | -1.6021425309 |
| GSE36640 | Down | -1.1662993971 |
| GSE54402 | Up | 0.1724522503 |
| GSE9593 | Down | -0.6232096632 |
| GSE43922 | Down | -0.6704463361 |
| GSE24585 | Down | -0.7352961257 |
| GSE37065 | Up | 0.0982190383 |
| GSE28863_A1 | Down | -0.2885695668 |
| GSE28863_A2 | Up | 0.5893973116 |
| GSE28863_A3 | Down | -0.2458898255 |
| GSE28863_A4 | Down | -0.0057052332 |
| GSE48662 | Down | -0.3198805635 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-520a-3p | MIMAT0002834 | MIRT007336 | Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 23389994 |
| hsa-miR-520b | MIMAT0002843 | MIRT007337 | Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 23389994 |
| hsa-miR-520e | MIMAT0002825 | MIRT007338 | Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 23389994 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030323 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-455-3p | MIMAT0004784 | MIRT037818 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039986 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041540 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
