HCSGD entry for PDE6A

1. General information

Official gene symbolPDE6A
Entrez ID5145
Gene full namephosphodiesterase 6A, cGMP-specific, rod, alpha
Other gene symbolsCGPR-A PDEA RP43
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0007596Blood coagulationTASbiological_process
GO:0007601Visual perceptionIEAbiological_process
GO:0007603Phototransduction, visible lightTASbiological_process
GO:0016056Rhodopsin mediated signaling pathwayTASbiological_process
GO:0022400Regulation of rhodopsin mediated signaling pathwayTASbiological_process
GO:0046037GMP metabolic processIMPbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:00475553',5'-cyclic-GMP phosphodiesterase activityIMPmolecular_function
GO:0051480Cytosolic calcium ion homeostasisIMPbiological_process
GO:0060041Retina development in camera-type eyeIEAbiological_process
GO:0097381Photoreceptor disc membraneTAScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.69217782000.84587362940.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1731885254
GSE13712_SHEARDown-0.0394905372
GSE13712_STATICUp0.1517894823
GSE19018Up0.0480519719
GSE19899_A1Down-0.0903134187
GSE19899_A2Down-0.1843174540
PubMed_21979375_A1Down-0.0445180570
PubMed_21979375_A2Down-0.0266852194
GSE35957Down-0.0310544345
GSE36640Down-0.0488055888
GSE54402Up0.1649530138
GSE9593Up0.1737841595
GSE43922Up0.0157653252
GSE24585Up0.0236224276
GSE37065Up0.0262427623
GSE28863_A1Down-0.0948444618
GSE28863_A2Up0.0882973466
GSE28863_A3Up0.0808876909
GSE28863_A4Up0.0496912432
GSE48662Up0.0685382255

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.