HCSGD entry for PDE6A

1. General information

Official gene symbolPDE6A
Entrez ID5145
Gene full namephosphodiesterase 6A, cGMP-specific, rod, alpha
Other gene symbolsCGPR-A PDEA RP43
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0007596Blood coagulationTASbiological_process
GO:0007601Visual perceptionIEAbiological_process
GO:0007603Phototransduction, visible lightTASbiological_process
GO:0016056Rhodopsin mediated signaling pathwayTASbiological_process
GO:0022400Regulation of rhodopsin mediated signaling pathwayTASbiological_process
GO:0046037GMP metabolic processIMPbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:00475553',5'-cyclic-GMP phosphodiesterase activityIMPmolecular_function
GO:0051480Cytosolic calcium ion homeostasisIMPbiological_process
GO:0060041Retina development in camera-type eyeIEAbiological_process
GO:0097381Photoreceptor disc membraneTAScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.69217782000.84587362940.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1731885254
GSE13712_SHEARDown-0.0394905372
GSE13712_STATICUp0.1517894823
GSE19018Up0.0480519719
GSE19899_A1Down-0.0903134187
GSE19899_A2Down-0.1843174540
PubMed_21979375_A1Down-0.0445180570
PubMed_21979375_A2Down-0.0266852194
GSE35957Down-0.0310544345
GSE36640Down-0.0488055888
GSE54402Up0.1649530138
GSE9593Up0.1737841595
GSE43922Up0.0157653252
GSE24585Up0.0236224276
GSE37065Up0.0262427623
GSE28863_A1Down-0.0948444618
GSE28863_A2Up0.0882973466
GSE28863_A3Up0.0808876909
GSE28863_A4Up0.0496912432
GSE48662Up0.0685382255

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.