HCSGD entry for ANAPC5
1. General information
| Official gene symbol | ANAPC5 |
|---|---|
| Entrez ID | 51433 |
| Gene full name | anaphase promoting complex subunit 5 |
| Other gene symbols | APC5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000086 | G2/M transition of mitotic cell cycle | TAS | biological_process |
| GO:0000090 | Mitotic anaphase | TAS | biological_process |
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0004842 | Ubiquitin-protein ligase activity | TAS | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005680 | Anaphase-promoting complex | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | TAS | biological_process |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0007094 | Mitotic spindle assembly checkpoint | TAS | biological_process |
| GO:0019903 | Protein phosphatase binding | IPI | molecular_function |
| GO:0031145 | Anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | TAS | biological_process |
| GO:0051436 | Negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | TAS | biological_process |
| GO:0051437 | Positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | TAS | biological_process |
| GO:0051439 | Regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | TAS | biological_process |
| GO:0070979 | Protein K11-linked ubiquitination | IDA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4939855097 | 0.4984423616 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3243606173 |
| GSE13712_SHEAR | Up | 0.0383108049 |
| GSE13712_STATIC | Down | -0.0408417298 |
| GSE19018 | Up | 0.0273977426 |
| GSE19899_A1 | Up | 0.0275276437 |
| GSE19899_A2 | Down | -0.1907629682 |
| PubMed_21979375_A1 | Down | -0.2247286332 |
| PubMed_21979375_A2 | Down | -0.3600438788 |
| GSE35957 | Down | -0.2542367946 |
| GSE36640 | Up | 0.1033760415 |
| GSE54402 | Up | 0.0473409189 |
| GSE9593 | Down | -0.0470611332 |
| GSE43922 | Up | 0.0181954309 |
| GSE24585 | Up | 0.0885178272 |
| GSE37065 | Down | -0.0939832948 |
| GSE28863_A1 | Up | 0.7987344402 |
| GSE28863_A2 | Up | 0.3641290281 |
| GSE28863_A3 | Down | -0.0541211406 |
| GSE28863_A4 | Down | -0.0885847356 |
| GSE48662 | Down | -0.4639194705 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022451 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1227-3p | MIMAT0005580 | MIRT036395 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-26b-3p | MIMAT0004500 | MIRT038955 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT047361 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048874 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT049952 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
