HCSGD entry for PDE4C

1. General information

Official gene symbolPDE4C
Entrez ID5143
Gene full namephosphodiesterase 4C, cAMP-specific
Other gene symbolsDPDE1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:00041143',5'-cyclic-nucleotide phosphodiesterase activityIEAmolecular_function
GO:00041153',5'-cyclic-AMP phosphodiesterase activityTASmolecular_function
GO:0005829CytosolTAScellular_component
GO:0006198CAMP catabolic processIEAbiological_process
GO:0007165Signal transductionIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0072372Primary ciliumIEA ISScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.39303449340.97056675660.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.1308317543
GSE28863_A2Down-0.0379269038
GSE28863_A3Up0.2441258335
GSE28863_A4Up0.0319673091
GSE48662Up0.2297067393

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

KetotifenDB00920 APRD01061
IloprostDB01088 APRD01027
RoflumilastDB01656 EXPT02802
PiclamilastDB01791 EXPT02600
AN2728DB05219 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.