HCSGD entry for PDE4C

1. General information

Official gene symbolPDE4C
Entrez ID5143
Gene full namephosphodiesterase 4C, cAMP-specific
Other gene symbolsDPDE1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:00041143',5'-cyclic-nucleotide phosphodiesterase activityIEAmolecular_function
GO:00041153',5'-cyclic-AMP phosphodiesterase activityTASmolecular_function
GO:0005829CytosolTAScellular_component
GO:0006198CAMP catabolic processIEAbiological_process
GO:0007165Signal transductionIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0072372Primary ciliumIEA ISScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.39303449340.97056675660.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.1308317543
GSE28863_A2Down-0.0379269038
GSE28863_A3Up0.2441258335
GSE28863_A4Up0.0319673091
GSE48662Up0.2297067393

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

KetotifenDB00920 APRD01061
IloprostDB01088 APRD01027
RoflumilastDB01656 EXPT02802
PiclamilastDB01791 EXPT02600
AN2728DB05219 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.