HCSGD entry for FZR1

1. General information

Official gene symbolFZR1
Entrez ID51343
Gene full namefizzy/cell division cycle 20 related 1 (Drosophila)
Other gene symbolsCDC20C CDH1 FZR FZR2 HCDH HCDH1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000278Mitotic cell cycleTASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005680Anaphase-promoting complexIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006281DNA repairIEAbiological_process
GO:0007067MitosisIEAbiological_process
GO:0008284Positive regulation of cell proliferationIEAbiological_process
GO:0031145Anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic processIDA TASbiological_process
GO:0031572G2 DNA damage checkpointIDAbiological_process
GO:0031965Nuclear membraneIDAcellular_component
GO:0040020Regulation of meiosisIEAbiological_process
GO:0045732Positive regulation of protein catabolic processIGIbiological_process
GO:0051436Negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051437Positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051439Regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051488Activation of anaphase-promoting complex activityIDAbiological_process
GO:0070306Lens fiber cell differentiationIEAbiological_process
GO:0070979Protein K11-linked ubiquitinationTASbiological_process
GO:0090344Negative regulation of cell agingIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.25847500470.93849829030.95225734661.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1052388591
GSE13712_SHEARUp0.2418021458
GSE13712_STATICUp0.1107419831
GSE19018Up0.0830264936
GSE19899_A1Up0.0053640924
GSE19899_A2Up0.0901108896
PubMed_21979375_A1Down-0.1201627186
PubMed_21979375_A2Up0.1543079064
GSE35957Down-0.0209198461
GSE36640Down-0.1249316329
GSE54402Up0.0848930000
GSE9593Up0.2307699781
GSE43922Up0.0474020143
GSE24585Down-0.0112950424
GSE37065Down-0.0452588901
GSE28863_A1Up0.1786931825
GSE28863_A2Up0.0926703125
GSE28863_A3Up0.2450371092
GSE28863_A4Up0.1193993459
GSE48662Up0.1481114953

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-744-5pMIMAT0004945MIRT037711CLASHFunctional MTI (Weak)23622248
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    • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-9-5pMIMAT0000441NAhsa-miR-9{phenotypic sensor assay}{endogenous}20173740
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.