HCSGD entry for FZR1

1. General information

Official gene symbolFZR1
Entrez ID51343
Gene full namefizzy/cell division cycle 20 related 1 (Drosophila)
Other gene symbolsCDC20C CDH1 FZR FZR2 HCDH HCDH1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000278Mitotic cell cycleTASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005680Anaphase-promoting complexIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006281DNA repairIEAbiological_process
GO:0007067MitosisIEAbiological_process
GO:0008284Positive regulation of cell proliferationIEAbiological_process
GO:0031145Anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic processIDA TASbiological_process
GO:0031572G2 DNA damage checkpointIDAbiological_process
GO:0031965Nuclear membraneIDAcellular_component
GO:0040020Regulation of meiosisIEAbiological_process
GO:0045732Positive regulation of protein catabolic processIGIbiological_process
GO:0051436Negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051437Positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051439Regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051488Activation of anaphase-promoting complex activityIDAbiological_process
GO:0070306Lens fiber cell differentiationIEAbiological_process
GO:0070979Protein K11-linked ubiquitinationTASbiological_process
GO:0090344Negative regulation of cell agingIEAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.25847500470.93849829030.95225734661.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1052388591
GSE13712_SHEARUp0.2418021458
GSE13712_STATICUp0.1107419831
GSE19018Up0.0830264936
GSE19899_A1Up0.0053640924
GSE19899_A2Up0.0901108896
PubMed_21979375_A1Down-0.1201627186
PubMed_21979375_A2Up0.1543079064
GSE35957Down-0.0209198461
GSE36640Down-0.1249316329
GSE54402Up0.0848930000
GSE9593Up0.2307699781
GSE43922Up0.0474020143
GSE24585Down-0.0112950424
GSE37065Down-0.0452588901
GSE28863_A1Up0.1786931825
GSE28863_A2Up0.0926703125
GSE28863_A3Up0.2450371092
GSE28863_A4Up0.1193993459
GSE48662Up0.1481114953

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-744-5pMIMAT0004945MIRT037711CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
  • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-9-5pMIMAT0000441NAhsa-miR-9{phenotypic sensor assay}{endogenous}20173740
Entries Per Page
Displaying Page of

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.