HCSGD entry for CDK18
1. General information
| Official gene symbol | CDK18 |
|---|---|
| Entrez ID | 5129 |
| Gene full name | cyclin-dependent kinase 18 |
| Other gene symbols | PCTAIRE PCTAIRE3 PCTK3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004672 | Protein kinase activity | IEA | molecular_function |
| GO:0004693 | Cyclin-dependent protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2441700657 | 0.9483022416 | 0.9325006671 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0021656082 |
| GSE13712_SHEAR | Up | 0.1160752542 |
| GSE13712_STATIC | Up | 0.2134120552 |
| GSE19018 | Up | 0.3329074351 |
| GSE19899_A1 | Up | 0.0325334810 |
| GSE19899_A2 | Up | 0.0785999586 |
| PubMed_21979375_A1 | Up | 0.3207376553 |
| PubMed_21979375_A2 | Up | 0.0344463709 |
| GSE35957 | Down | -0.2552423842 |
| GSE36640 | Up | 0.0548642615 |
| GSE54402 | Down | -0.0211552020 |
| GSE9593 | Down | -0.0888040630 |
| GSE43922 | Up | 0.0545814397 |
| GSE24585 | Up | 0.3286095288 |
| GSE37065 | Down | -0.0676340617 |
| GSE28863_A1 | Down | -0.0531141845 |
| GSE28863_A2 | Up | 0.4868987668 |
| GSE28863_A3 | Up | 0.2465412706 |
| GSE28863_A4 | Up | 0.0553075944 |
| GSE48662 | Down | -0.0149175874 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017648 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029346 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046594 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
