HCSGD entry for CDK18


1. General information

Official gene symbolCDK18
Entrez ID5129
Gene full namecyclin-dependent kinase 18
Other gene symbolsPCTAIRE PCTAIRE3 PCTK3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004672Protein kinase activityIEAmolecular_function
GO:0004693Cyclin-dependent protein serine/threonine kinase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005575Cellular_componentNDcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.24417006570.94830224160.93250066711.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0021656082
GSE13712_SHEARUp0.1160752542
GSE13712_STATICUp0.2134120552
GSE19018Up0.3329074351
GSE19899_A1Up0.0325334810
GSE19899_A2Up0.0785999586
PubMed_21979375_A1Up0.3207376553
PubMed_21979375_A2Up0.0344463709
GSE35957Down-0.2552423842
GSE36640Up0.0548642615
GSE54402Down-0.0211552020
GSE9593Down-0.0888040630
GSE43922Up0.0545814397
GSE24585Up0.3286095288
GSE37065Down-0.0676340617
GSE28863_A1Down-0.0531141845
GSE28863_A2Up0.4868987668
GSE28863_A3Up0.2465412706
GSE28863_A4Up0.0553075944
GSE48662Down-0.0149175874

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017648MicroarrayFunctional MTI (Weak)18185580
hsa-miR-26b-5pMIMAT0000083MIRT029346MicroarrayFunctional MTI (Weak)19088304
hsa-miR-222-3pMIMAT0000279MIRT046594CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.