HCSGD entry for VRK3
1. General information
| Official gene symbol | VRK3 |
|---|---|
| Entrez ID | 51231 |
| Gene full name | vaccinia related kinase 3 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004672 | Protein kinase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0019903 | Protein phosphatase binding | IEA | molecular_function |
| GO:0032516 | Positive regulation of phosphoprotein phosphatase activity | IEA | biological_process |
| GO:0070373 | Negative regulation of ERK1 and ERK2 cascade | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2408433760 | 0.9304280726 | 0.9276284899 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1207791141 |
| GSE13712_SHEAR | Up | 0.0853324908 |
| GSE13712_STATIC | Up | 0.1676956508 |
| GSE19018 | Up | 0.0430715217 |
| GSE19899_A1 | Down | -0.0313792554 |
| GSE19899_A2 | Up | 0.5844192499 |
| PubMed_21979375_A1 | Up | 0.3544292262 |
| PubMed_21979375_A2 | Up | 0.6518521016 |
| GSE35957 | Down | -0.0816458486 |
| GSE36640 | Up | 0.2076835535 |
| GSE54402 | Up | 0.1664707743 |
| GSE9593 | Up | 0.1450483276 |
| GSE43922 | Down | -0.0147362877 |
| GSE24585 | Down | -0.0144841849 |
| GSE37065 | Up | 0.0490643033 |
| GSE28863_A1 | Down | -0.0296474068 |
| GSE28863_A2 | Down | -0.2754248437 |
| GSE28863_A3 | Down | -0.4043433250 |
| GSE28863_A4 | Up | 0.0982060627 |
| GSE48662 | Up | 0.3405491423 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
