HCSGD entry for VRK3

1. General information

Official gene symbolVRK3
Entrez ID51231
Gene full namevaccinia related kinase 3
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004672Protein kinase activityIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0019903Protein phosphatase bindingIEAmolecular_function
GO:0032516Positive regulation of phosphoprotein phosphatase activityIEAbiological_process
GO:0070373Negative regulation of ERK1 and ERK2 cascadeIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.24084337600.93042807260.92762848991.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1207791141
GSE13712_SHEARUp0.0853324908
GSE13712_STATICUp0.1676956508
GSE19018Up0.0430715217
GSE19899_A1Down-0.0313792554
GSE19899_A2Up0.5844192499
PubMed_21979375_A1Up0.3544292262
PubMed_21979375_A2Up0.6518521016
GSE35957Down-0.0816458486
GSE36640Up0.2076835535
GSE54402Up0.1664707743
GSE9593Up0.1450483276
GSE43922Down-0.0147362877
GSE24585Down-0.0144841849
GSE37065Up0.0490643033
GSE28863_A1Down-0.0296474068
GSE28863_A2Down-0.2754248437
GSE28863_A3Down-0.4043433250
GSE28863_A4Up0.0982060627
GSE48662Up0.3405491423

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.