HCSGD entry for SLC45A2
1. General information
| Official gene symbol | SLC45A2 |
|---|---|
| Entrez ID | 51151 |
| Gene full name | solute carrier family 45, member 2 |
| Other gene symbols | 1A1 AIM1 MATP SHEP5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0007601 | Visual perception | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0033162 | Melanosome membrane | IEA | cellular_component |
| GO:0042438 | Melanin biosynthetic process | IEA | biological_process |
| GO:0048066 | Developmental pigmentation | IEA | biological_process |
| GO:0050896 | Response to stimulus | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5495051822 | 0.9482718020 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0187884894 |
| GSE13712_SHEAR | Up | 0.0412939415 |
| GSE13712_STATIC | Up | 0.1127930762 |
| GSE19018 | Up | 0.2169855329 |
| GSE19899_A1 | Up | 0.0639619019 |
| GSE19899_A2 | Down | -0.0002761916 |
| PubMed_21979375_A1 | Down | -0.0256973906 |
| PubMed_21979375_A2 | Down | -0.0731464218 |
| GSE35957 | Up | 0.1133803148 |
| GSE36640 | Up | 0.1173721172 |
| GSE54402 | Up | 0.0852910705 |
| GSE9593 | Down | -0.0214638391 |
| GSE43922 | Up | 0.0420945304 |
| GSE24585 | Up | 0.2112483609 |
| GSE37065 | Up | 0.0038330627 |
| GSE28863_A1 | Up | 0.0411907061 |
| GSE28863_A2 | Down | -0.0059710238 |
| GSE28863_A3 | Up | 0.1082920838 |
| GSE28863_A4 | Up | 0.0859907702 |
| GSE48662 | Up | 0.0248849333 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 27104887 | WD induced a NASH phenotype in OLETFs characterized by hepatic fibrosis (collagen 1alpha1 mRNA and hydroxyproline content), as well as elevated inflammation and non-alcoholic fatty liver disease activity scores, and hepatic stellate cell activation (alpha-smooth muscle actin) compared to Long-Evans Tokushima Otsuka rats |
| 19487283 | The other elongation factor, eukaryotic translation elongation factor 1alpha1 (eEF1A1), was also down-regulated |
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