HCSGD entry for SLC45A2


1. General information

Official gene symbolSLC45A2
Entrez ID51151
Gene full namesolute carrier family 45, member 2
Other gene symbols1A1 AIM1 MATP SHEP5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0007601Visual perceptionIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0033162Melanosome membraneIEAcellular_component
GO:0042438Melanin biosynthetic processIEAbiological_process
GO:0048066Developmental pigmentationIEAbiological_process
GO:0050896Response to stimulusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.54950518220.94827180200.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0187884894
GSE13712_SHEARUp0.0412939415
GSE13712_STATICUp0.1127930762
GSE19018Up0.2169855329
GSE19899_A1Up0.0639619019
GSE19899_A2Down-0.0002761916
PubMed_21979375_A1Down-0.0256973906
PubMed_21979375_A2Down-0.0731464218
GSE35957Up0.1133803148
GSE36640Up0.1173721172
GSE54402Up0.0852910705
GSE9593Down-0.0214638391
GSE43922Up0.0420945304
GSE24585Up0.2112483609
GSE37065Up0.0038330627
GSE28863_A1Up0.0411907061
GSE28863_A2Down-0.0059710238
GSE28863_A3Up0.1082920838
GSE28863_A4Up0.0859907702
GSE48662Up0.0248849333

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

27104887WD induced a NASH phenotype in OLETFs characterized by hepatic fibrosis (collagen 1alpha1 mRNA and hydroxyproline content), as well as elevated inflammation and non-alcoholic fatty liver disease activity scores, and hepatic stellate cell activation (alpha-smooth muscle actin) compared to Long-Evans Tokushima Otsuka rats
19487283The other elongation factor, eukaryotic translation elongation factor 1alpha1 (eEF1A1), was also down-regulated
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