HCSGD entry for RPS27L

1. General information

Official gene symbolRPS27L
Entrez ID51065
Gene full nameribosomal protein S27-like
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003735Structural constituent of ribosomeIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005840RibosomeIEAcellular_component
GO:0006281DNA repairIMPbiological_process
GO:0006412TranslationIDA IEAbiological_process
GO:0006417Regulation of translationIDAbiological_process
GO:0006919Activation of cysteine-type endopeptidase activity involved in apoptotic processIDAbiological_process
GO:0006974Cellular response to DNA damage stimulusIDAbiological_process
GO:0008494Translation activator activityIDAmolecular_function
GO:0008656Cysteine-type endopeptidase activator activity involved in apoptotic processIDAmolecular_function
GO:0010952Positive regulation of peptidase activityIDAbiological_process
GO:0031571Mitotic G1 DNA damage checkpointIMPbiological_process
GO:0042771Intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorIDAbiological_process
GO:0043085Positive regulation of catalytic activityIDAbiological_process
GO:0043281Regulation of cysteine-type endopeptidase activity involved in apoptotic processIDAbiological_process
GO:0045727Positive regulation of translationIDAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0050790Regulation of catalytic activityIDAbiological_process
GO:0052547Regulation of peptidase activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03387217430.64307552140.42392490491.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0890307747
GSE13712_SHEARUp0.0588376293
GSE13712_STATICUp0.0574464362
GSE19018Up0.7861146704
GSE19899_A1Up0.2390949872
GSE19899_A2Up0.5086057404
PubMed_21979375_A1Up0.1643249325
PubMed_21979375_A2Up0.2821807362
GSE35957Up0.5962183666
GSE36640Up0.3464598786
GSE54402Down-0.1553024882
GSE9593Up0.5369202915
GSE43922Down-0.0537553023
GSE24585Up0.3336029755
GSE37065Up0.3148927487
GSE28863_A1Up0.2830920067
GSE28863_A2Down-0.3398248872
GSE28863_A3Down-1.4791249838
GSE28863_A4Up0.0995115531
GSE48662Down-0.0074064876

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-484MIMAT0002174MIRT041935CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.