HCSGD entry for RPS27L

1. General information

Official gene symbolRPS27L
Entrez ID51065
Gene full nameribosomal protein S27-like
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003735Structural constituent of ribosomeIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005840RibosomeIEAcellular_component
GO:0006281DNA repairIMPbiological_process
GO:0006412TranslationIDA IEAbiological_process
GO:0006417Regulation of translationIDAbiological_process
GO:0006919Activation of cysteine-type endopeptidase activity involved in apoptotic processIDAbiological_process
GO:0006974Cellular response to DNA damage stimulusIDAbiological_process
GO:0008494Translation activator activityIDAmolecular_function
GO:0008656Cysteine-type endopeptidase activator activity involved in apoptotic processIDAmolecular_function
GO:0010952Positive regulation of peptidase activityIDAbiological_process
GO:0031571Mitotic G1 DNA damage checkpointIMPbiological_process
GO:0042771Intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorIDAbiological_process
GO:0043085Positive regulation of catalytic activityIDAbiological_process
GO:0043281Regulation of cysteine-type endopeptidase activity involved in apoptotic processIDAbiological_process
GO:0045727Positive regulation of translationIDAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0050790Regulation of catalytic activityIDAbiological_process
GO:0052547Regulation of peptidase activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03387217430.64307552140.42392490491.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0890307747
GSE13712_SHEARUp0.0588376293
GSE13712_STATICUp0.0574464362
GSE19018Up0.7861146704
GSE19899_A1Up0.2390949872
GSE19899_A2Up0.5086057404
PubMed_21979375_A1Up0.1643249325
PubMed_21979375_A2Up0.2821807362
GSE35957Up0.5962183666
GSE36640Up0.3464598786
GSE54402Down-0.1553024882
GSE9593Up0.5369202915
GSE43922Down-0.0537553023
GSE24585Up0.3336029755
GSE37065Up0.3148927487
GSE28863_A1Up0.2830920067
GSE28863_A2Down-0.3398248872
GSE28863_A3Down-1.4791249838
GSE28863_A4Up0.0995115531
GSE48662Down-0.0074064876

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-484MIMAT0002174MIRT041935CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.