HCSGD entry for SPOCK3


1. General information

Official gene symbolSPOCK3
Entrez ID50859
Gene full namesparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
Other gene symbolsHSAJ1454 TES-3 TICN3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005539Glycosaminoglycan bindingIEAmolecular_function
GO:0005578Proteinaceous extracellular matrixIEAcellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0007165Signal transductionIEAbiological_process
GO:0008191Metalloendopeptidase inhibitor activityIDA IEAmolecular_function
GO:0010951Negative regulation of endopeptidase activityIDAbiological_process
GO:0019800Peptide cross-linking via chondroitin 4-sulfate glycosaminoglycanIEAbiological_process
GO:0031012Extracellular matrixIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.53296291930.86315938220.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1814700877
GSE13712_SHEARDown-0.0909335171
GSE13712_STATICDown-0.3867370666
GSE19018Up0.1153213827
GSE19899_A1Up0.1432036451
GSE19899_A2Up0.0452750025
PubMed_21979375_A1Down-0.0878526977
PubMed_21979375_A2Up0.1202077134
GSE35957Up0.0954987667
GSE36640Up0.0569176483
GSE54402Up0.0970771696
GSE9593Up0.0396628866
GSE43922Up0.0110117443
GSE24585Up0.3567962485
GSE37065Down-0.0396905487
GSE28863_A1Down-0.0573538838
GSE28863_A2Up0.0488643204
GSE28863_A3Up0.1721342864
GSE28863_A4Down-0.0215593647
GSE48662Down-0.0268845261

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.