HCSGD entry for PAFAH1B3
1. General information
| Official gene symbol | PAFAH1B3 |
|---|---|
| Entrez ID | 5050 |
| Gene full name | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| Other gene symbols | PAFAHG |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003847 | 1-alkyl-2-acetylglycerophosphocholine esterase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0006629 | Lipid metabolic process | TAS | biological_process |
| GO:0007283 | Spermatogenesis | IEA | biological_process |
| GO:0007399 | Nervous system development | TAS | biological_process |
| GO:0007420 | Brain development | IEA | biological_process |
| GO:0016042 | Lipid catabolic process | IEA | biological_process |
| GO:0016787 | Hydrolase activity | IEA | molecular_function |
| GO:0046982 | Protein heterodimerization activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9728927624 | 0.0074211238 | 0.9999902473 | 0.1724019417 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1034759717 |
| GSE13712_SHEAR | Down | -0.4765025652 |
| GSE13712_STATIC | Down | -0.0461146861 |
| GSE19018 | Down | -0.1645792877 |
| GSE19899_A1 | Down | -0.7048962021 |
| GSE19899_A2 | Down | -0.6881913431 |
| PubMed_21979375_A1 | Up | 0.1388834178 |
| PubMed_21979375_A2 | Down | -0.7925267791 |
| GSE35957 | Down | -1.4935552310 |
| GSE36640 | Down | -1.0144638947 |
| GSE54402 | Up | 0.1010837568 |
| GSE9593 | Down | -0.5864651266 |
| GSE43922 | Down | -0.5040520750 |
| GSE24585 | Down | -0.3576026803 |
| GSE37065 | Up | 0.0638610651 |
| GSE28863_A1 | Down | -0.3130942126 |
| GSE28863_A2 | Down | -0.0855275926 |
| GSE28863_A3 | Up | 0.2844929796 |
| GSE28863_A4 | Up | 0.1616966951 |
| GSE48662 | Down | -0.7517876135 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| (1R)-1,2,2-TRIMETHYLPROPYL (R)-METHYLPHOSPHINATE | DB07821 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023703 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032358 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-23a-3p | MIMAT0000078 | MIRT050436 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
