HCSGD entry for OTX1

1. General information

Official gene symbolOTX1
Entrez ID5013
Gene full nameorthodenticle homeobox 1
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006357Regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0009952Anterior/posterior pattern specificationIEAbiological_process
GO:0022037Metencephalon developmentIEAbiological_process
GO:0030901Midbrain developmentIEAbiological_process
GO:0042472Inner ear morphogenesisIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0048852Diencephalon morphogenesisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.88456785080.70033653360.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0865161011
GSE13712_SHEARDown-0.0823711825
GSE13712_STATICDown-0.0438938018
GSE19018Down-0.0450612130
GSE19899_A1Up0.0013662447
GSE19899_A2Up0.0787528572
PubMed_21979375_A1Down-0.1039304941
PubMed_21979375_A2Down-0.2397825813
GSE35957Up0.1011909617
GSE36640Down-0.0715909030
GSE54402Up0.0043192732
GSE9593Up0.0229581157
GSE43922Up0.0356865109
GSE24585Up0.0010408513
GSE37065Down-0.0867823708
GSE28863_A1Up0.0131486350
GSE28863_A2Down-0.0047047998
GSE28863_A3Up0.2858141861
GSE28863_A4Up0.0291202066
GSE48662Up0.0756071692

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-375MIMAT0000728MIRT020057MicroarrayFunctional MTI (Weak)20215506
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.