HCSGD entry for OTX1
1. General information
| Official gene symbol | OTX1 |
|---|---|
| Entrez ID | 5013 |
| Gene full name | orthodenticle homeobox 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0009952 | Anterior/posterior pattern specification | IEA | biological_process |
| GO:0022037 | Metencephalon development | IEA | biological_process |
| GO:0030901 | Midbrain development | IEA | biological_process |
| GO:0042472 | Inner ear morphogenesis | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0048852 | Diencephalon morphogenesis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8845678508 | 0.7003365336 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0865161011 |
| GSE13712_SHEAR | Down | -0.0823711825 |
| GSE13712_STATIC | Down | -0.0438938018 |
| GSE19018 | Down | -0.0450612130 |
| GSE19899_A1 | Up | 0.0013662447 |
| GSE19899_A2 | Up | 0.0787528572 |
| PubMed_21979375_A1 | Down | -0.1039304941 |
| PubMed_21979375_A2 | Down | -0.2397825813 |
| GSE35957 | Up | 0.1011909617 |
| GSE36640 | Down | -0.0715909030 |
| GSE54402 | Up | 0.0043192732 |
| GSE9593 | Up | 0.0229581157 |
| GSE43922 | Up | 0.0356865109 |
| GSE24585 | Up | 0.0010408513 |
| GSE37065 | Down | -0.0867823708 |
| GSE28863_A1 | Up | 0.0131486350 |
| GSE28863_A2 | Down | -0.0047047998 |
| GSE28863_A3 | Up | 0.2858141861 |
| GSE28863_A4 | Up | 0.0291202066 |
| GSE48662 | Up | 0.0756071692 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT020057 | Microarray | Functional MTI (Weak) | 20215506 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
