HCSGD entry for OPRM1

1. General information

Official gene symbolOPRM1
Entrez ID4988
Gene full nameopioid receptor, mu 1
Other gene symbolsLMOR M-OR-1 MOP MOR MOR1 OPRM
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001965G-protein alpha-subunit bindingIDAmolecular_function
GO:0004930G-protein coupled receptor activityISSmolecular_function
GO:0004979Beta-endorphin receptor activityIEA IMPmolecular_function
GO:0005245Voltage-gated calcium channel activityISSmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005783Endoplasmic reticulumTAScellular_component
GO:0005794Golgi apparatusTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006810TransportISSbiological_process
GO:0006812Cation transportISSbiological_process
GO:0007187G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerTASbiological_process
GO:0007191Adenylate cyclase-activating dopamine receptor signaling pathwayIEAbiological_process
GO:0007193Adenylate cyclase-inhibiting G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0007194Negative regulation of adenylate cyclase activityISSbiological_process
GO:0007200Phospholipase C-activating G-protein coupled receptor signaling pathwayISSbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationIDAbiological_process
GO:0007218Neuropeptide signaling pathwayIMPbiological_process
GO:0007268Synaptic transmissionIMPbiological_process
GO:0007600Sensory perceptionNASbiological_process
GO:0007610BehaviorNASbiological_process
GO:0007626Locomotory behaviorIEAbiological_process
GO:0008285Negative regulation of cell proliferationTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0019233Sensory perception of painISSbiological_process
GO:0030001Metal ion transportISSbiological_process
GO:0033554Cellular response to stressIMPbiological_process
GO:0034220Ion transmembrane transportISSbiological_process
GO:0038047Morphine receptor activityISSmolecular_function
GO:0043950Positive regulation of cAMP-mediated signalingIDAbiological_process
GO:0043951Negative regulation of cAMP-mediated signalingIDAbiological_process
GO:0045019Negative regulation of nitric oxide biosynthetic processIDAbiological_process
GO:0045429Positive regulation of nitric oxide biosynthetic processIDAbiological_process
GO:0048149Behavioral response to ethanolIMPbiological_process
GO:0050769Positive regulation of neurogenesisISSbiological_process
GO:0050795Regulation of behaviorIMPbiological_process
GO:0051481Negative regulation of cytosolic calcium ion concentrationIDAbiological_process
GO:0055085Transmembrane transportISSbiological_process
GO:0061358Negative regulation of Wnt protein secretionIMPbiological_process
GO:0070374Positive regulation of ERK1 and ERK2 cascadeISSbiological_process
GO:0070588Calcium ion transmembrane transportISSbiological_process
GO:0072511Divalent inorganic cation transportISSbiological_process
GO:2000310Regulation of N-methyl-D-aspartate selective glutamate receptor activityISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.85387078760.86480250750.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0414092910
GSE13712_SHEARUp0.0839583206
GSE13712_STATICDown-0.0106659831
GSE19018Up0.0176376810
GSE19899_A1Up0.0261485797
GSE19899_A2Down-0.0004853084
PubMed_21979375_A1Down-0.0652501704
PubMed_21979375_A2Up0.0363800295
GSE35957Up0.0497104748
GSE36640Up0.0004585689
GSE54402Up0.0412994869
GSE9593Down-0.0787154743
GSE43922Up0.0050151692
GSE24585Up0.0000812630
GSE37065Up0.0592139954
GSE28863_A1Down-0.0470569238
GSE28863_A2Up0.1218181324
GSE28863_A3Up0.1031468915
GSE28863_A4Up0.0258928129
GSE48662Up0.0551277472

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-let-7a-5pMIMAT0000062NAhsa-let-7a{Western blot}{downregulation by anti-miRNA oligonucleotide}20668208
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.