HCSGD entry for OAS3
1. General information
| Official gene symbol | OAS3 |
|---|---|
| Entrez ID | 4940 |
| Gene full name | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| Other gene symbols | p100 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001730 | 2'-5'-oligoadenylate synthetase activity | IDA | molecular_function |
| GO:0003725 | Double-stranded RNA binding | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IDA IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006139 | Nucleobase-containing compound metabolic process | TAS | biological_process |
| GO:0006955 | Immune response | IEA | biological_process |
| GO:0009615 | Response to virus | IDA | biological_process |
| GO:0016740 | Transferase activity | IEA | molecular_function |
| GO:0019221 | Cytokine-mediated signaling pathway | TAS | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | TAS | cellular_component |
| GO:0045071 | Negative regulation of viral genome replication | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051607 | Defense response to virus | IDA IEA | biological_process |
| GO:0060333 | Interferon-gamma-mediated signaling pathway | TAS | biological_process |
| GO:0060337 | Type I interferon signaling pathway | TAS | biological_process |
| GO:0060700 | Regulation of ribonuclease activity | IDA | biological_process |
Entries Per Page
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0172503970 | 0.0734392766 | 0.3231956584 | 0.5103431626 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0168665362 |
| GSE13712_SHEAR | Up | 2.9669318889 |
| GSE13712_STATIC | Up | 1.5642104066 |
| GSE19018 | Up | 0.1910277739 |
| GSE19899_A1 | Down | -0.1024396893 |
| GSE19899_A2 | Down | -0.5186263562 |
| PubMed_21979375_A1 | Down | -0.9421263367 |
| PubMed_21979375_A2 | Down | -0.6779797657 |
| GSE35957 | Down | -2.2265720062 |
| GSE36640 | Down | -0.4799071708 |
| GSE54402 | Down | -0.5261939980 |
| GSE9593 | Down | -0.2307817461 |
| GSE43922 | Down | -0.2705339488 |
| GSE24585 | Up | 1.4372130596 |
| GSE37065 | Up | 1.6339988879 |
| GSE28863_A1 | Up | 0.1037627914 |
| GSE28863_A2 | Up | 1.6129303843 |
| GSE28863_A3 | Up | 0.1012394245 |
| GSE28863_A4 | Up | 0.0793510258 |
| GSE48662 | Down | -0.0569087758 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
