HCSGD entry for CISD2
1. General information
| Official gene symbol | CISD2 |
|---|---|
| Entrez ID | 493856 |
| Gene full name | CDGSH iron sulfur domain 2 |
| Other gene symbols | ERIS Miner1 NAF-1 WFS2 ZCD2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000422 | Mitochondrion degradation | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005741 | Mitochondrial outer membrane | ISS | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IDA | cellular_component |
| GO:0010259 | Multicellular organismal aging | ISS | biological_process |
| GO:0010506 | Regulation of autophagy | IMP | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0042803 | Protein homodimerization activity | IDA | molecular_function |
| GO:0043231 | Intracellular membrane-bounded organelle | IEA | cellular_component |
| GO:0043234 | Protein complex | IDA | cellular_component |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051537 | 2 iron, 2 sulfur cluster binding | IDA IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9359422742 | 0.1666194256 | 0.9999902473 | 0.7891393127 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0040245089 |
| GSE13712_SHEAR | Down | -0.1486455532 |
| GSE13712_STATIC | Down | -0.0602524004 |
| GSE19018 | Down | -0.3682437165 |
| GSE19899_A1 | Up | 0.0555806699 |
| GSE19899_A2 | Down | -0.1851935300 |
| PubMed_21979375_A1 | Down | -0.1711468105 |
| PubMed_21979375_A2 | Down | -0.4587067091 |
| GSE35957 | Down | -0.2386099669 |
| GSE36640 | Down | -0.5043539482 |
| GSE54402 | Up | 0.1749092147 |
| GSE9593 | Up | 0.0098538784 |
| GSE43922 | Down | -0.1291707491 |
| GSE24585 | Down | -0.0668356425 |
| GSE37065 | Up | 0.4407128732 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.0298570122 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020662 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-455-3p | MIMAT0004784 | MIRT037876 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-182-5p | MIMAT0000259 | MIRT047175 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
