HCSGD entry for CISD2


1. General information

Official gene symbolCISD2
Entrez ID493856
Gene full nameCDGSH iron sulfur domain 2
Other gene symbolsERIS Miner1 NAF-1 WFS2 ZCD2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000422Mitochondrion degradationIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005741Mitochondrial outer membraneISScellular_component
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005789Endoplasmic reticulum membraneIDAcellular_component
GO:0010259Multicellular organismal agingISSbiological_process
GO:0010506Regulation of autophagyIMPbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0043231Intracellular membrane-bounded organelleIEAcellular_component
GO:0043234Protein complexIDAcellular_component
GO:0046872Metal ion bindingIEAmolecular_function
GO:00515372 iron, 2 sulfur cluster bindingIDA IEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.93594227420.16661942560.99999024730.7891393127

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0040245089
GSE13712_SHEARDown-0.1486455532
GSE13712_STATICDown-0.0602524004
GSE19018Down-0.3682437165
GSE19899_A1Up0.0555806699
GSE19899_A2Down-0.1851935300
PubMed_21979375_A1Down-0.1711468105
PubMed_21979375_A2Down-0.4587067091
GSE35957Down-0.2386099669
GSE36640Down-0.5043539482
GSE54402Up0.1749092147
GSE9593Up0.0098538784
GSE43922Down-0.1291707491
GSE24585Down-0.0668356425
GSE37065Up0.4407128732
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.0298570122

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT020662ProteomicsFunctional MTI (Weak)18668040
hsa-miR-455-3pMIMAT0004784MIRT037876CLASHFunctional MTI (Weak)23622248
hsa-miR-182-5pMIMAT0000259MIRT047175CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.