HCSGD entry for NEUROD2

1. General information

Official gene symbolNEUROD2
Entrez ID4761
Gene full nameneuronal differentiation 2
Other gene symbolsNDRF bHLHa1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001662Behavioral fear responseIEAbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityTASmolecular_function
GO:0003714Transcription corepressor activityISSmolecular_function
GO:0005634NucleusISScellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0007399Nervous system developmentTASbiological_process
GO:0008306Associative learningIEAbiological_process
GO:0016567Protein ubiquitinationISSbiological_process
GO:0021695Cerebellar cortex developmentISSbiological_process
GO:0031915Positive regulation of synaptic plasticityISSbiological_process
GO:0045666Positive regulation of neuron differentiationISSbiological_process
GO:0046982Protein heterodimerization activityISSmolecular_function
GO:0048666Neuron developmentIEAbiological_process
GO:0050850Positive regulation of calcium-mediated signalingISSbiological_process
GO:0051091Positive regulation of sequence-specific DNA binding transcription factor activityISSbiological_process
GO:0070888E-box bindingISSmolecular_function
GO:0071257Cellular response to electrical stimulusISSbiological_process
GO:0071277Cellular response to calcium ionISSbiological_process
GO:0090129Positive regulation of synapse maturationISSbiological_process
GO:2000297Negative regulation of synapse maturationISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.73383719460.80599336270.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0223690035
GSE13712_SHEARDown-0.0245504046
GSE13712_STATICUp0.1816066867
GSE19018Up0.0461011272
GSE19899_A1Up0.0186968242
GSE19899_A2Up0.1579480891
PubMed_21979375_A1Down-0.0212714318
PubMed_21979375_A2Down-0.1066295280
GSE35957Up0.0182910306
GSE36640Up0.1037391306
GSE54402Down-0.0255021367
GSE9593Down-0.0424119313
GSE43922Up0.0921698137
GSE24585Up0.0114185333
GSE37065Down-0.0722223498
GSE28863_A1Down-0.2571154251
GSE28863_A2Down-0.1310773738
GSE28863_A3Up0.2939344717
GSE28863_A4Up0.0537085994
GSE48662Up0.0457162484

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018380MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.