HCSGD entry for ATOH1

1. General information

Official gene symbolATOH1
Entrez ID474
Gene full nameatonal homolog 1 (Drosophila)
Other gene symbolsATH1 HATH1 MATH-1 bHLHa14
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001764Neuron migrationIEAbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityTASmolecular_function
GO:0005634NucleusISScellular_component
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0007411Axon guidanceIEAbiological_process
GO:0007417Central nervous system developmentTASbiological_process
GO:0021987Cerebral cortex developmentIEAbiological_process
GO:0031490Chromatin DNA bindingIEAmolecular_function
GO:0042472Inner ear morphogenesisIEAbiological_process
GO:0042667Auditory receptor cell fate specificationIEAbiological_process
GO:0042668Auditory receptor cell fate determinationIEAbiological_process
GO:0043066Negative regulation of apoptotic processIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045609Positive regulation of auditory receptor cell differentiationIEAbiological_process
GO:0045666Positive regulation of neuron differentiationISSbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0046983Protein dimerization activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.75030544810.73426309410.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0095664488
GSE13712_SHEARUp0.0107636875
GSE13712_STATICUp0.1784599767
GSE19018Down-0.0752847039
GSE19899_A1Down-0.2120739760
GSE19899_A2Up0.0400189944
PubMed_21979375_A1Up0.0821702447
PubMed_21979375_A2Down-0.0687917602
GSE35957Up0.0050819058
GSE36640Up0.1333319919
GSE54402Down-0.0367559507
GSE9593Up0.0759124410
GSE43922Up0.0287012054
GSE24585Down-0.0369020281
GSE37065Down-0.0776830961
GSE28863_A1Down-0.0344260790
GSE28863_A2Up0.0582283457
GSE28863_A3Up0.1047695051
GSE28863_A4Up0.1866341027
GSE48662Down-0.0100261789

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017641MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.