HCSGD entry for ATOH1

1. General information

Official gene symbolATOH1
Entrez ID474
Gene full nameatonal homolog 1 (Drosophila)
Other gene symbolsATH1 HATH1 MATH-1 bHLHa14
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001764Neuron migrationIEAbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityTASmolecular_function
GO:0005634NucleusISScellular_component
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0007411Axon guidanceIEAbiological_process
GO:0007417Central nervous system developmentTASbiological_process
GO:0021987Cerebral cortex developmentIEAbiological_process
GO:0031490Chromatin DNA bindingIEAmolecular_function
GO:0042472Inner ear morphogenesisIEAbiological_process
GO:0042667Auditory receptor cell fate specificationIEAbiological_process
GO:0042668Auditory receptor cell fate determinationIEAbiological_process
GO:0043066Negative regulation of apoptotic processIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045609Positive regulation of auditory receptor cell differentiationIEAbiological_process
GO:0045666Positive regulation of neuron differentiationISSbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0046983Protein dimerization activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.75030544810.73426309410.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0095664488
GSE13712_SHEARUp0.0107636875
GSE13712_STATICUp0.1784599767
GSE19018Down-0.0752847039
GSE19899_A1Down-0.2120739760
GSE19899_A2Up0.0400189944
PubMed_21979375_A1Up0.0821702447
PubMed_21979375_A2Down-0.0687917602
GSE35957Up0.0050819058
GSE36640Up0.1333319919
GSE54402Down-0.0367559507
GSE9593Up0.0759124410
GSE43922Up0.0287012054
GSE24585Down-0.0369020281
GSE37065Down-0.0776830961
GSE28863_A1Down-0.0344260790
GSE28863_A2Up0.0582283457
GSE28863_A3Up0.1047695051
GSE28863_A4Up0.1866341027
GSE48662Down-0.0100261789

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017641MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.