HCSGD entry for NDUFS6


1. General information

Official gene symbolNDUFS6
Entrez ID4726
Gene full nameNADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
Other gene symbolsCI-13kA CI-13kD-A CI13KDA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005743Mitochondrial inner membraneTAScellular_component
GO:0005747Mitochondrial respiratory chain complex IIDA NAScellular_component
GO:0006120Mitochondrial electron transport, NADH to ubiquinoneNASbiological_process
GO:0006631Fatty acid metabolic processIEAbiological_process
GO:0006936Muscle contractionIEAbiological_process
GO:0008137NADH dehydrogenase (ubiquinone) activityNASmolecular_function
GO:0009055Electron carrier activityNASmolecular_function
GO:0010259Multicellular organismal agingIEAbiological_process
GO:0022904Respiratory electron transport chainTASbiological_process
GO:0035264Multicellular organism growthIEAbiological_process
GO:0044237Cellular metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0061458Reproductive system developmentIEAbiological_process
GO:0070584Mitochondrion morphogenesisIEAbiological_process
GO:0072358Cardiovascular system developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.61684845560.46755347440.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.6632584258
GSE13712_SHEARDown-0.0819503718
GSE13712_STATICDown-0.0051549051
GSE19018Up0.1455758433
GSE19899_A1Down-0.2682134223
GSE19899_A2Up0.0406726224
PubMed_21979375_A1Down-0.0072994776
PubMed_21979375_A2Down-0.0585978110
GSE35957Down-0.1654603717
GSE36640Down-0.2028055162
GSE54402Up0.1980252113
GSE9593Down-0.2738459678
GSE43922Up0.0221702148
GSE24585Down-0.1273581747
GSE37065Up0.0023980717
GSE28863_A1Down-0.0822834709
GSE28863_A2Down-0.1294555558
GSE28863_A3Up0.1891166686
GSE28863_A4Up0.0404380948
GSE48662Down-0.0542442977

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NADHDB00157 NUTR00041 | DB01907 | EXPT02287 | DB03527

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-193b-3pMIMAT0002819MIRT041397CLASHFunctional MTI (Weak)23622248
hsa-miR-27b-3pMIMAT0000419MIRT046190CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.