HCSGD entry for NDUFS6
1. General information
| Official gene symbol | NDUFS6 |
|---|---|
| Entrez ID | 4726 |
| Gene full name | NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) |
| Other gene symbols | CI-13kA CI-13kD-A CI13KDA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005743 | Mitochondrial inner membrane | TAS | cellular_component |
| GO:0005747 | Mitochondrial respiratory chain complex I | IDA NAS | cellular_component |
| GO:0006120 | Mitochondrial electron transport, NADH to ubiquinone | NAS | biological_process |
| GO:0006631 | Fatty acid metabolic process | IEA | biological_process |
| GO:0006936 | Muscle contraction | IEA | biological_process |
| GO:0008137 | NADH dehydrogenase (ubiquinone) activity | NAS | molecular_function |
| GO:0009055 | Electron carrier activity | NAS | molecular_function |
| GO:0010259 | Multicellular organismal aging | IEA | biological_process |
| GO:0022904 | Respiratory electron transport chain | TAS | biological_process |
| GO:0035264 | Multicellular organism growth | IEA | biological_process |
| GO:0044237 | Cellular metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0061458 | Reproductive system development | IEA | biological_process |
| GO:0070584 | Mitochondrion morphogenesis | IEA | biological_process |
| GO:0072358 | Cardiovascular system development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6168484556 | 0.4675534744 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.6632584258 |
| GSE13712_SHEAR | Down | -0.0819503718 |
| GSE13712_STATIC | Down | -0.0051549051 |
| GSE19018 | Up | 0.1455758433 |
| GSE19899_A1 | Down | -0.2682134223 |
| GSE19899_A2 | Up | 0.0406726224 |
| PubMed_21979375_A1 | Down | -0.0072994776 |
| PubMed_21979375_A2 | Down | -0.0585978110 |
| GSE35957 | Down | -0.1654603717 |
| GSE36640 | Down | -0.2028055162 |
| GSE54402 | Up | 0.1980252113 |
| GSE9593 | Down | -0.2738459678 |
| GSE43922 | Up | 0.0221702148 |
| GSE24585 | Down | -0.1273581747 |
| GSE37065 | Up | 0.0023980717 |
| GSE28863_A1 | Down | -0.0822834709 |
| GSE28863_A2 | Down | -0.1294555558 |
| GSE28863_A3 | Up | 0.1891166686 |
| GSE28863_A4 | Up | 0.0404380948 |
| GSE48662 | Down | -0.0542442977 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041397 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-27b-3p | MIMAT0000419 | MIRT046190 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
