HCSGD entry for NCF4

1. General information

Official gene symbolNCF4
Entrez ID4689
Gene full nameneutrophil cytosolic factor 4, 40kDa
Other gene symbolsNCF P40PHOX SH3PXD4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002474Antigen processing and presentation of peptide antigen via MHC class ITASbiological_process
GO:0002479Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependentTASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005829CytosolIDA TAScellular_component
GO:0006955Immune responseTASbiological_process
GO:0007154Cell communicationIEAbiological_process
GO:0010008Endosome membraneIDAcellular_component
GO:0016020MembraneIDAcellular_component
GO:0016176Superoxide-generating NADPH oxidase activator activityIMPmolecular_function
GO:0032010PhagolysosomeTAScellular_component
GO:0032266Phosphatidylinositol-3-phosphate bindingIDAmolecular_function
GO:0035091Phosphatidylinositol bindingIEAmolecular_function
GO:0042590Antigen processing and presentation of exogenous peptide antigen via MHC class ITASbiological_process
GO:0043020NADPH oxidase complexIDAcellular_component
GO:0043085Positive regulation of catalytic activityIMPbiological_process
GO:0046983Protein dimerization activityTASmolecular_function
GO:0050790Regulation of catalytic activityIMPbiological_process
GO:0051701Interaction with hostTASbiological_process
GO:0055114Oxidation-reduction processTASbiological_process
GO:0090382Phagosome maturationTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.57824599370.77266924510.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0250100198
GSE13712_SHEARDown-0.0125072386
GSE13712_STATICDown-0.0993541199
GSE19018Up0.1923126219
GSE19899_A1Up0.0648373157
GSE19899_A2Up0.2620045622
PubMed_21979375_A1Up0.0883011843
PubMed_21979375_A2Up0.0348463780
GSE35957Up0.3523930215
GSE36640Down-0.0093327112
GSE54402Up0.0960059022
GSE9593Down-0.0414617902
GSE43922Down-0.1274745020
GSE24585Up0.1453670702
GSE37065Down-0.0356321616
GSE28863_A1Down-0.1991101493
GSE28863_A2Down-0.1046706535
GSE28863_A3Up0.1176330054
GSE28863_A4Down-0.0275963485
GSE48662Up0.1321167123

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

DextromethorphanDB00514 APRD00655

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017337MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.