HCSGD entry for NAIP
1. General information
| Official gene symbol | NAIP |
|---|---|
| Entrez ID | 4671 |
| Gene full name | NLR family, apoptosis inhibitory protein |
| Other gene symbols | BIRC1 NLRB1 psiNAIP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004869 | Cysteine-type endopeptidase inhibitor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA IMP | molecular_function |
| GO:0005737 | Cytoplasm | ISS | cellular_component |
| GO:0006954 | Inflammatory response | IEA | biological_process |
| GO:0007399 | Nervous system development | TAS | biological_process |
| GO:0016323 | Basolateral plasma membrane | ISS | cellular_component |
| GO:0017111 | Nucleoside-triphosphatase activity | IEA | molecular_function |
| GO:0043066 | Negative regulation of apoptotic process | ISS | biological_process |
| GO:0043154 | Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | IDA | biological_process |
| GO:0043524 | Negative regulation of neuron apoptotic process | TAS | biological_process |
| GO:0045087 | Innate immune response | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8029760989 | 0.2293669351 | 0.9999902473 | 0.9218693740 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0068793751 |
| GSE13712_SHEAR | Up | 0.3922417392 |
| GSE13712_STATIC | Up | 0.0330219585 |
| GSE19018 | Down | -0.1560552515 |
| GSE19899_A1 | Up | 0.0212036481 |
| GSE19899_A2 | Down | -0.5758083726 |
| PubMed_21979375_A1 | Down | -0.3315311049 |
| PubMed_21979375_A2 | Down | -0.1823705488 |
| GSE35957 | Up | 0.0245838257 |
| GSE36640 | Down | -0.3182145135 |
| GSE54402 | Up | 0.1486947709 |
| GSE9593 | Down | -0.1158713719 |
| GSE43922 | Down | -0.3447860395 |
| GSE24585 | Up | 0.1319996066 |
| GSE37065 | Up | 0.2025138290 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.0820078335 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-221-3p | MIMAT0000278 | MIRT005295 | Western blot | Functional MTI | 18759060 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
