HCSGD entry for NAIP


1. General information

Official gene symbolNAIP
Entrez ID4671
Gene full nameNLR family, apoptosis inhibitory protein
Other gene symbolsBIRC1 NLRB1 psiNAIP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004869Cysteine-type endopeptidase inhibitor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEA IMPmolecular_function
GO:0005737CytoplasmISScellular_component
GO:0006954Inflammatory responseIEAbiological_process
GO:0007399Nervous system developmentTASbiological_process
GO:0016323Basolateral plasma membraneISScellular_component
GO:0017111Nucleoside-triphosphatase activityIEAmolecular_function
GO:0043066Negative regulation of apoptotic processISSbiological_process
GO:0043154Negative regulation of cysteine-type endopeptidase activity involved in apoptotic processIDAbiological_process
GO:0043524Negative regulation of neuron apoptotic processTASbiological_process
GO:0045087Innate immune responseIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.80297609890.22936693510.99999024730.9218693740

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0068793751
GSE13712_SHEARUp0.3922417392
GSE13712_STATICUp0.0330219585
GSE19018Down-0.1560552515
GSE19899_A1Up0.0212036481
GSE19899_A2Down-0.5758083726
PubMed_21979375_A1Down-0.3315311049
PubMed_21979375_A2Down-0.1823705488
GSE35957Up0.0245838257
GSE36640Down-0.3182145135
GSE54402Up0.1486947709
GSE9593Down-0.1158713719
GSE43922Down-0.3447860395
GSE24585Up0.1319996066
GSE37065Up0.2025138290
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.0820078335

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-221-3pMIMAT0000278MIRT005295Western blotFunctional MTI18759060
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.