HCSGD entry for TRIM37
1. General information
| Official gene symbol | TRIM37 |
|---|---|
| Entrez ID | 4591 |
| Gene full name | tripartite motif containing 37 |
| Other gene symbols | MUL POB1 TEF3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005164 | Tumor necrosis factor receptor binding | IPI | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005777 | Peroxisome | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016235 | Aggresome | IDA | cellular_component |
| GO:0031625 | Ubiquitin protein ligase binding | IPI | molecular_function |
| GO:0032088 | Negative regulation of NF-kappaB transcription factor activity | IDA | biological_process |
| GO:0042803 | Protein homodimerization activity | IDA | molecular_function |
| GO:0046600 | Negative regulation of centriole replication | IMP | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
| GO:0051865 | Protein autoubiquitination | IDA | biological_process |
| GO:0070842 | Aggresome assembly | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1306279587 | 0.2635140914 | 0.7340432323 | 0.9853759091 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1979244873 |
| GSE13712_SHEAR | Up | 0.5274995272 |
| GSE13712_STATIC | Up | 0.9256921931 |
| GSE19018 | Up | 0.0416444023 |
| GSE19899_A1 | Down | -0.4244177740 |
| GSE19899_A2 | Down | -0.0342543190 |
| PubMed_21979375_A1 | Up | 0.9158417277 |
| PubMed_21979375_A2 | Down | -0.2860161051 |
| GSE35957 | Down | -0.1714103788 |
| GSE36640 | Down | -0.2211693572 |
| GSE54402 | Up | 0.3021718316 |
| GSE9593 | Up | 0.2621758454 |
| GSE43922 | Down | -0.3407724953 |
| GSE24585 | Up | 0.4133033156 |
| GSE37065 | Up | 0.0457161487 |
| GSE28863_A1 | Down | -0.2767311566 |
| GSE28863_A2 | Up | 0.2549949126 |
| GSE28863_A3 | Down | -0.8236260229 |
| GSE28863_A4 | Up | 0.2512589879 |
| GSE48662 | Down | -0.4374774718 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022999 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-769-3p | MIMAT0003887 | MIRT039127 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30e-3p | MIMAT0000693 | MIRT044117 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-183-5p | MIMAT0000261 | MIRT047093 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
