HCSGD entry for TRIM37


1. General information

Official gene symbolTRIM37
Entrez ID4591
Gene full nametripartite motif containing 37
Other gene symbolsMUL POB1 TEF3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004842Ubiquitin-protein ligase activityIDAmolecular_function
GO:0005164Tumor necrosis factor receptor bindingIPImolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005777PeroxisomeIDAcellular_component
GO:0005829CytosolIDAcellular_component
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0016235AggresomeIDAcellular_component
GO:0031625Ubiquitin protein ligase bindingIPImolecular_function
GO:0032088Negative regulation of NF-kappaB transcription factor activityIDAbiological_process
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0046600Negative regulation of centriole replicationIMPbiological_process
GO:0048471Perinuclear region of cytoplasmIEAcellular_component
GO:0051865Protein autoubiquitinationIDAbiological_process
GO:0070842Aggresome assemblyIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.13062795870.26351409140.73404323230.9853759091

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1979244873
GSE13712_SHEARUp0.5274995272
GSE13712_STATICUp0.9256921931
GSE19018Up0.0416444023
GSE19899_A1Down-0.4244177740
GSE19899_A2Down-0.0342543190
PubMed_21979375_A1Up0.9158417277
PubMed_21979375_A2Down-0.2860161051
GSE35957Down-0.1714103788
GSE36640Down-0.2211693572
GSE54402Up0.3021718316
GSE9593Up0.2621758454
GSE43922Down-0.3407724953
GSE24585Up0.4133033156
GSE37065Up0.0457161487
GSE28863_A1Down-0.2767311566
GSE28863_A2Up0.2549949126
GSE28863_A3Down-0.8236260229
GSE28863_A4Up0.2512589879
GSE48662Down-0.4374774718

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022999MicroarrayFunctional MTI (Weak)18668037
hsa-miR-769-3pMIMAT0003887MIRT039127CLASHFunctional MTI (Weak)23622248
hsa-miR-30e-3pMIMAT0000693MIRT044117CLASHFunctional MTI (Weak)23622248
hsa-miR-183-5pMIMAT0000261MIRT047093CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.