HCSGD entry for MUC2

1. General information

Official gene symbolMUC2
Entrez ID4583
Gene full namemucin 2, oligomeric mucus/gel-forming
Other gene symbolsMLP MUC-2 SMUC
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002064Epithelial cell developmentIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005578Proteinaceous extracellular matrixIEAcellular_component
GO:0005796Golgi lumenTAScellular_component
GO:0006915Apoptotic processIEAbiological_process
GO:0008285Negative regulation of cell proliferationIEAbiological_process
GO:0016266O-glycan processingTASbiological_process
GO:0030336Negative regulation of cell migrationIEAbiological_process
GO:0043065Positive regulation of apoptotic processIEAbiological_process
GO:0043687Post-translational protein modificationTASbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0070702Inner mucus layerIEA ISScellular_component
GO:0070703Outer mucus layerIEA ISScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.73725071240.71738886060.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0322531541
GSE13712_SHEARDown-0.0797804544
GSE13712_STATICDown-0.2721319161
GSE19018Up0.0052392889
GSE19899_A1Up0.0144481123
GSE19899_A2Up0.0872137088
PubMed_21979375_A1Down-0.0552539995
PubMed_21979375_A2Down-0.0991635255
GSE35957Up0.1610324650
GSE36640Up0.0246585307
GSE54402Down-0.2410784246
GSE9593Up0.1461600164
GSE43922Up0.0844175406
GSE24585Down-0.0235947663
GSE37065Down-0.0505631139
GSE28863_A1Down-0.0697591679
GSE28863_A2Down-0.0823799818
GSE28863_A3Up0.3328559389
GSE28863_A4Up0.1117108068
GSE48662Up0.2285984649

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

PranlukastDB01411 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.