HCSGD entry for MUC2


1. General information

Official gene symbolMUC2
Entrez ID4583
Gene full namemucin 2, oligomeric mucus/gel-forming
Other gene symbolsMLP MUC-2 SMUC
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002064Epithelial cell developmentIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005578Proteinaceous extracellular matrixIEAcellular_component
GO:0005796Golgi lumenTAScellular_component
GO:0006915Apoptotic processIEAbiological_process
GO:0008285Negative regulation of cell proliferationIEAbiological_process
GO:0016266O-glycan processingTASbiological_process
GO:0030336Negative regulation of cell migrationIEAbiological_process
GO:0043065Positive regulation of apoptotic processIEAbiological_process
GO:0043687Post-translational protein modificationTASbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0070702Inner mucus layerIEA ISScellular_component
GO:0070703Outer mucus layerIEA ISScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.73725071240.71738886060.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0322531541
GSE13712_SHEARDown-0.0797804544
GSE13712_STATICDown-0.2721319161
GSE19018Up0.0052392889
GSE19899_A1Up0.0144481123
GSE19899_A2Up0.0872137088
PubMed_21979375_A1Down-0.0552539995
PubMed_21979375_A2Down-0.0991635255
GSE35957Up0.1610324650
GSE36640Up0.0246585307
GSE54402Down-0.2410784246
GSE9593Up0.1461600164
GSE43922Up0.0844175406
GSE24585Down-0.0235947663
GSE37065Down-0.0505631139
GSE28863_A1Down-0.0697591679
GSE28863_A2Down-0.0823799818
GSE28863_A3Up0.3328559389
GSE28863_A4Up0.1117108068
GSE48662Up0.2285984649

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

PranlukastDB01411 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.